Any cell that passes through the aperture will momentarily increase the resistance of the electrical flow between the electrodes, generating a pulse. This principle is known as what?

The principle described in the question refers to the concept of electrical impedance, which is a measure of how much a circuit resists the flow of electrical current when a voltage is applied. In the context of hematology, this principle is often utilized in automated cell counters, where cells passing through an aperture disrupt an electric field, causing a change in resistance that generates a measurable pulse. This pulse is directly proportional to the size of the cell and is used for counting and analyzing cells in a sample.

Electrical impedance encompasses both resistive and reactive components, making it a more comprehensive concept than simply resistance alone. It is significant in various applications, including medical diagnostics, where the physical properties of cells can be inferred from changes in electrical impedance as they move through a defined area.

In summary, the generation of a pulse from changes in electrical flow due to cellular passage through an aperture exemplifies the principles of electrical impedance, aligning with how automated hemocytometers operate in hematology practices.