Panhyperplasia of the bone marrow is associated with which anemia?

Prepare your best for the AAB MT Hematology Exam. Utilize flashcards and multiple choice questions, complete with explanations and hints. Ace the exam!

Panhyperplasia of the bone marrow is characterized by an increase in the number of cells in all hematopoietic lineages, indicating that the body is producing more red blood cells, white blood cells, and platelets. This condition is commonly associated with polycythemia vera, which is a myeloproliferative neoplasm where the body produces excess red blood cells due to a mutation in the hematopoietic stem cells.

In polycythemia vera, the increased red blood cell mass leads to higher blood viscosity and can cause a variety of symptoms, including headaches, dizziness, and an increased risk of thrombosis. The panhyperplastic state of the bone marrow reflects the systemic overproduction of blood components, which is a hallmark of this disorder.

In contrast, other anemias listed in the choices have different underlying mechanisms. Aplastic anemia is characterized by a deficiency of all blood cell types due to failed hematopoiesis, leading to a hypoplastic or empty bone marrow. Sickle cell anemia results from a genetic mutation that causes red blood cells to become misshapen and does not involve hyperplasia of the marrow. Iron deficiency anemia is related to insufficient iron for hemoglobin production, typically leading to microcy

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