What cellular characterizations are most utilized in systems employing laser light scatter?

The most commonly utilized cellular characterizations in systems employing laser light scatter are granularity and reflectivity. This technique is based on the principles of light scattering, where a laser beam is directed at cells. As the cells pass through the beam, they scatter light in different directions, and this scattering provides valuable information about each cell's characteristics.

Granularity refers to the internal structures and complexity of the cells, which influences how light interacts with them. More granular cells scatter light differently than smoother, less granular cells, allowing for differentiation based on internal components like granules or organelles.

Reflectivity is related to how light is refracted or reflected from the surface of the cells, which can indicate additional characteristics such as cell surface properties and membrane integrity.

Collectively, analyzing these two properties allows for effective identification and classification of various cell types, which is crucial in hematology for diagnosing conditions, counting cells, and characterizing blood samples.