What is the inactive form of plasmin called?

The inactive form of plasmin is known as plasminogen. This precursor plays a crucial role in the body's fibrinolytic system, which is responsible for the breakdown of fibrin in blood clots. When a clot is formed, plasminogen is incorporated into the clot and remains inactive until it is activated by various factors, including tissue plasminogen activator (tPA) or urokinase. Once activated, plasminogen converts into plasmin, which has the enzymatic ability to dissolve fibrin clots, thereby restoring normal blood flow.

Understanding the function of plasminogen is essential in hematology and has clinical implications, particularly in conditions related to thrombosis and clot management. This knowledge is fundamental for medical technologists who need to understand the dynamics of clot formation and resolution in the body.