What is the normal plasma concentration of fibrinogen?

The normal plasma concentration of fibrinogen typically ranges from 200 to 400 mg/dL, with many sources indicating that the average is about 300 mg/dL. Fibrinogen is a critical protein in the blood coagulation process, as it is converted into fibrin during clot formation. This makes its concentration vital for proper clotting function and overall hemostasis.

Values above or below this normal range can indicate various health conditions. For instance, low fibrinogen levels might be seen in conditions such as liver disease or disseminated intravascular coagulation, while high levels may indicate inflammation or acute phase reactions. Thus, the understanding of normal fibrinogen levels is crucial for diagnosing and managing hematological disorders.