Which bleeding disorder is characterized by mucous membrane bleeding and can have prolonged PT and PTT?

Prepare your best for the AAB MT Hematology Exam. Utilize flashcards and multiple choice questions, complete with explanations and hints. Ace the exam!

The bleeding disorder characterized by mucous membrane bleeding and potential prolongation of both PT (prothrombin time) and PTT (partial thromboplastin time) is disseminated intravascular coagulopathy (DIC). In DIC, there is an overactivation of the coagulation cascade, which leads to widespread formation of blood clots within small blood vessels. This process consumes clotting factors and platelets, leading to a paradoxical increased risk of bleeding.

Mucous membrane bleeding is common in cases of DIC, as the consumptive coagulopathy can lead to a deficiency in both clotting factors involved in the intrinsic and extrinsic pathways, resulting in prolonged PT and PTT values. The simultaneous activation of clotting factors and platelets can lead to bleeding manifestations due to the depletion of these critical components.

Other options mention conditions that have distinct characteristics. Hemophilia typically results in only prolonged PTT due to deficiencies in intrinsic pathway factors and does not specifically present with mucous membrane bleeding. Von Willebrand's disease leads to bleeding tendencies due to issues with platelet function and often presents with mucocutaneous bleeding but is more associated with a prolonged PTT than PT. Thrombocytopenic purpura primarily

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