Which of the following is NOT a finding in chronic lymphocytic leukemia?

In chronic lymphocytic leukemia (CLL), hypercalcemia is not a typical finding. This condition is characterized primarily by an accumulation of small, mature lymphocytes which leads to elevated lymphocyte counts, known as lymphocytosis. The presence of smudge cells, which are damaged lymphocytes that often occur due to fragile cell membranes during the slide preparation, is a hallmark of CLL.

Additionally, bone marrow infiltration is integral to the disease as the neoplastic proliferation of lymphocytes infiltrates the marrow, leading to a decreased ability to produce normal blood cells. Hypercalcemia is more commonly associated with other malignancies or conditions, such as multiple myeloma or certain solid tumors. Thus, the presence of hypercalcemia is not a finding typically associated with chronic lymphocytic leukemia, reinforcing why this answer is correct.