Which of the following statements about hemoglobin D disease is true?

Hemoglobin D disease is typically considered a mild condition resulting from the presence of hemoglobin D, which is an atypical form of hemoglobin. Individuals with this condition often do not experience significant health issues and may have no symptoms or only mild anemia. This mild nature and the fact that it is relatively rare among the hemoglobinopathies make this statement accurate.

Hemoglobin D disease usually does not lead to the severe complications that are associated with other hemoglobinopathies, such as sickle cell disease or thalassemia. While there may be cases where individuals might experience some mild symptoms, the majority are asymptomatic and maintain normal health. This characteristic supports the assertion that it is usually harmless.

The other options present more severe implications for the condition, either by suggesting a greater prevalence or health impact, which does not align with the clinical understanding of hemoglobin D disease.