Which stain is known to stain both specific and nonspecific granules in myelogenous cells?

Prepare your best for the AAB MT Hematology Exam. Utilize flashcards and multiple choice questions, complete with explanations and hints. Ace the exam!

The correct choice for identifying a stain that affects both specific and nonspecific granules in myelogenous cells is the Giemsa stain. Giemsa stain is widely used in hematology for the visualization of blood cells and provides comprehensive differentiation of cellular components. It effectively stains various granules, allowing for the identification of myelogenous lineage. This stain highlights the different cellular components, including both the specific granules (such as those found in neutrophils) and nonspecific granules, thus offering detailed insight into the morphology of myeloid cells.

Other stains, such as Prussian blue, are primarily used to detect iron deposits, while hematoxylin and eosin are more general stains that don't specifically target granules in myelogenous cells. Wright's stain is similar to Giemsa but does not provide the same depth of granule differentiation as Giemsa, making it less effective for this specific application. This characteristic makes Giemsa stain particularly valuable in clinical settings for diagnosing hematological disorders.

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