Which type of white blood cell can appear with toxic granulation?

Toxic granulation is a phenomenon typically associated with neutrophils, which are a type of white blood cell vital for the body's immune response against infections. When neutrophils respond to acute inflammation or infection, their granules can become more prominent and darker. This change, referred to as toxic granulation, reflects the neutrophils' heightened state of activity and their role in fighting off pathogens.

In clinical settings, the presence of toxic granulation in neutrophils can be indicative of several conditions, such as bacterial infections, inflammatory processes, or other stressors affecting the immune system. The granules themselves contain various enzymes and proteins that help break down bacteria and other foreign materials, which becomes especially important during an active immune response.

Other types of white blood cells, such as basophils, eosinophils, and lymphocytes, do not typically exhibit toxic granulation. Each has distinct characteristics and roles in the immune response but lacks the marked enlargement and toxicity seen in activated neutrophils during acute inflammatory events. Therefore, neutrophils are recognized for the occurrence of toxic granulation, making this the correct response to the question.